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ypdA [2019-07-04 13:09:57]
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ypdA [2019-07-04 13:09:57]

putative bacillithiol reductase
locus
BSU22950
pI
6.08
mw
36.18 kDa
protein length
324 aa Sequence Blast
gene length
975 bp Sequence Blast
function
recycling of oxidized bacillithiol disulfide to the reduced form (BSH)
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]

    • Gene

    Coordinates
    2,400,984 → 2,401,958

    The protein

    Catalyzed reaction/ biological activity

  • recycling of oxidized bacillithiol disulfide (BSSB) to the reduced form (BSH) [pubmed|30636083]

    • Protein family

  • Trx reductase family

    • Structure

  • [PDB|4ZN0] (from Methanosarcina mazei, 27% identity)

    • [SW|Localization]

  • cell membrane (according to Swiss-Prot)

    • Biological materials

    Mutant

  • MGNA-A398 (ypdA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/398 NBRP B. subtilis, Japan]
  • BKE22950 (Δ[gene|FF7440B70CCB5A9C443944E0259D845A958EA279|ypdA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE22950 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCTGTCAACTCCTGCG, downstream forward: _UP4_TAAAGATGAGGAGCATATGA
  • BKK22950 (Δ[gene|FF7440B70CCB5A9C443944E0259D845A958EA279|ypdA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK22950 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCTGTCAACTCCTGCG, downstream forward: _UP4_TAAAGATGAGGAGCATATGA

    • References

  • 20308541,30636083